Denzel Washington and Chris Pine star in this suspenseful action thriller that's based on a real-life incident involving a runaway train. Not only does the locomotive have toxic chemicals aboard, it's also picking up speed as it heads toward a populated area - the area in which Colson (Pine) lives with his wife and young son. As a horrified public looks on, Barnes (Washington) and Colman take on the task of stopping the runaway train before it causes a deadly catastrophe.